Department of Pharmacology
The department is having highly dedicated, qualified and experienced staff actively involved in research at UG, PG and Ph.D. levels. This is unique place to disseminate the upgraded information on the molecular basis of some of the diseases which are challenge to society till date. We strive to bridge the gap between modern science and traditional knowledge through up graded skills and techniques in the research. The laboratories are very well equipped and enriched with ultra-modern facilities designed according to the norms of statutory body. The sophisticated instruments available with us are Auto-analyzer, BIOPAC, Cooling centrifuge, Plethysmometer (Hugo-Basile,Italy) , analytical balance etc. The department is involved in active research at molecular level in preclinical screening of lead molecules from synthetic as well as natural origin.
Department of Pharmacology
The department is having highly dedicated, qualified and experienced staff actively involved in research at UG, PG and Ph.D. levels. This is unique place to disseminate the upgraded information on the molecular basis of some of the diseases which are challenge to society till date. We strive to bridge the gap between modern science and traditional knowledge through up graded skills and techniques in the research. The laboratories are very well equipped and enriched with ultra-modern facilities designed according to the norms of statutory body. The sophisticated instruments available with us are Auto-analyzer, BIOPAC, Cooling centrifuge, Plethysmometer (Hugo-Basile,Italy) , analytical balance etc. The department is involved in active research at molecular level in preclinical screening of lead molecules from synthetic as well as natural origin.
Areas Of Research
Central Nervous system disorders
- Depression
- Cognitive deficit
- Anxiety
- Convulsions
- Parkinsonism
Cardiovascular Disorders like
- Arrhythmia
- Hypertension
- Hyperlipidemia and atherosclerosis
Diabetes and its related complications
- Cardiopathy
- Neuropathy
- Nephropathy
- Erectile dysfunction
- Immune dysfunction
Inflammatory complications
- Rheumatoid and
- Anti-inflammatory.
Gastrointestinal tract disorders
- Diarrhea, Ulcer
Respiratory system disorders
- Asthma
Reproductive system disorders
- Sexual dysfunction, Anti-fertility
Animal House Facility
The animal house under Pharmacology Department is approved by CPCSEA (Committee for the Purpose of Control and Supervision of Experiments on Animals), New Delhi for research activity. The recognition number is No. 198/CPCSEA. The animal house facility is available to meet the growing need of high quality laboratory animals in emergent field of Experimental Pharmacology.
 | Dr. Shirish JainM. Pharm., Ph.D.| >>View Profile<< |
 | Dr. Sanjay KastureM. Pharm., Ph.D. Post Doc.| Professor| >>View Profile<< |
 | Dr. Yogita MundhadaM. Pharm., Ph.D.| Professor | Department : Pharmacology >>View Profile<< |
 | Mr. Sachin BorikarM. Pharm. | Assistant Professor | >>View Profile<< |
 | Miss. Manisha JawaleM. Pharm.|Assistant Professor| >>View Profile<< |
 | Miss. Meena BhalakeM. Pharm.|Assistant Professor| >>View Profile<< |
  | Mr. Ashish TaleM.Pharm. | Assistant Professor | Department : Pharmacology >>View Profile<< |
 | Miss. Kashmira MalusareM. Pharm.|Assistant Professor| >>View Profile<< |
 | Miss. Vaishnavi PatilM. Pharm.|Assistant Professor| >>View Profile<< |
PUBLICATIONS
Sr No. | Name of Author | Title of Research Work | Name of Journal | Publication Year | ISSN No | Impact Factor |
1. | Siying Lin, Aida Sanchez-Bretaño, Joseph S Leslie, Katie B Williams, Helena Lee, N Simon Thomas, Jonathan Callaway, James Deline, J Arjuna Ratnayaka, Diana Baralle, Melanie A Schmitt, Chelsea S Norman, Sheri Hammond, Gaurav V Harlalka, Sarah Ennis, Harold E Cross, Olivia Wenger, Andrew H Crosby, Emma L Baple, Jay E Self | Evidence that the Ser192Tyr/Arg402Gln in cis Tyrosinase gene haplotype is a disease-causing allele in oculocutaneous albinism type 1B (OCA1B) | (Nature Partner Journals) NPJ Genomic Medicine | 2022 | 2056-7944 (Electronic) 2056-7944 (Linking) | 7.227 |
2. | Iftikhar Ahmed, Muhammad Ilyas, Gaurav V Harlalka, Asif Mir | A Novel Hemizygous Variant in the AFF2 Gene Causing Fragile XE (FRAXE) Syndrome: First Report from Pakistan | Pakistan Journal of Medical Research | 2021 | ISSN : 0300-9842 | 0.98 |
3. | Kamal Khan, Sarmad Mehmood, Chunyu Liu, Maimoona Siddiqui, Arsalan Ahmad, Belqees Yawar Faiz, Barry A Chioza, Emma L Baple, Muhammad I Ullah, Zaineb Akram, Humayoon S Satti, Raees Khan, Gaurav V Harlalka, Muhammad Jameel, Talia Akram, Shahid M Baig, Andrew H Crosby, Muhammad J Hassan, Feng Zhang, Erica E Davis, Tahir N Khan | A recurrent rare intronic variant in CAPN3 alters mRNA splicing and causes autosomal recessive limb-girdle muscular dystrophy-1 in three Pakistani pedigrees | Am J Med Genet A | 2021 | ISSN: 1552-4825 (Print) ISSN: 1552-4833 (Electronic) ISSN: 1552-4825 (Linking) | 2.802 |
4. | Abida Akbar, Muneeba Bint-E-Farrakh, Andrew H Crosby, Asma Gul, Gaurav V Harlalka | Variants in NIPAL4 and ALOXE3 cause autosomal recessive congenital ichthyosis in Pakistani families | Congenit Anom (Kyoto) | 2020 | ISSN: 0914-3505 (Print) ISSN: 1741-4520 (Electronic) ISSN: 0914-3505 (Linking) | 1.409
|
5. | Abida Akbar, Claire Prince, Chloe Payne, James Fasham, Wasim Ahmad, Emma L Baple, Andrew H Crosby, Gaurav V Harlalka, Asma Gul | Novel nonsense variants in SLURP1 and DSG1 cause palmoplantar keratoderma in Pakistani families | BMC Med Genet | 2019 | 1471-2350 (Electronic) | 1.988 |
6. | Shazia Khan, Lettie E Rawlins, Gaurav V Harlalka, Muhammad Umair, Asmat Ullah, Shaheen Shahzad, Muhammad Javed, Emma L Baple, Andrew H Crosby, Wasim Ahmad, Asma Gul | Homozygous variants in the HEXB and MBOAT7 genes underlie neurological diseases in consanguineous families | BMC Med Genet | 2019 | 1471-2350 (Electronic) | 1.988 |
7. | Sumit Rathod, Mangesh Deokar, Vinay Bhalerao, Dr.Shirish Jain | Role of Lysine in ethanol induced behavioral changes in mice | International Journal of toxicological and Pharmacological Research | Accepted for Publication
| ISSN No 09755160 | 1.773 |
Information will be available soon.
AWARDS AND ACHIEVEMENTS
Dr. Gaurav Harlalka
- Resource person for academicians and students for delivering session on “genetics of two different forms, SPG26 and SPG57, of hereditary spastic paraplegia” at Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), Delhi on 28th January 2021.
- Resource person at Faculty Development Program under the scheme of PMMMNMTT (Sponsored by MHRD, Govt. of India & Supported by RUSA, and conducted by ICT, Mumbai), organized at Rajarshi Shahu College of Pharmacy, Buldana, in November 2019.
- Resource person at workshop entitled “Screening techniques in experimental pharmacology 2.0” which was sponsored by Indian Pharmacological Society at R C Patel College of Pharmacy, Shirpur, Dhule in September 2019.
- Guest lecture delivered at H R Patel College of Pharmacy in September 2019.
- Received “Best Poster Award” by Royal Society of Chemistry Conference entitled Chemical & Biological Therapeutic Approaches to Neurological Disorders II, London, UK in September 2013.
- N M Wadia Scholarship in August 2006.
- N M Wadia Scholarship in August 2005.
- Qualified National Level GATE-2005 organised by IIT, Mumbai.
- Prof G G Bahaley Gold Medal awarded by Anuradha College of Pharmacy, Chikhli, Buldana.
Mr. Mangesh Narayan Deokar
- Resource person for Maharashtra State Pharmacy Council’s (MSPC) Drug Information Centre, Mumbai Organised Patient Counselling Course (PCC) for Registered pharmacist which held at different places in Buldana Distinct as
- At Patient Counselling Course (PCC) on topic Medication Error in dispensing medicine in drug stores at Shegaon District Buldana on date 27/05/2017
- At Patient Counselling Course (PCC) on topic Physiology of Hypertension for patients counselling at Buldana District Buldana on date 29/05/2017
- At Patient Counselling Course (PCC) on topic Role of Cholesterol in diet for patent counselling. at Akola District Akola on date 10/08/2017
- At Patient Counselling Course (PCC) on topic Medical Adherence for patient counselling. at Khamgaon District Buldana on date 12/11/2017
- At Patient Counselling Course (PCC) on topic Roles of Meals and Medicine for patient counselling. at Sangrampur District Buldana on date 21/11/2017
- At Patient Counselling Course (PCC) on topic Patient Instruction for counselling.at Sakharkharda District Buldana on date 12/02/2018
- Organised International Yoga Day as Yoga Trainer at Rajarshi Shahu College of Pharmacy Buldanaon 21th June 2017
- Organised International Yoga Day as Yoga Trainer at District Homegard Department at Buldana on 21th June 2018
Department activities
Webinars conducted
Coordinator: Dr. Gaurav Harlalka, Mr. Mangesh Deokar Convener: Dr. Shirish Jain
Sr. No. | Topic of webinar | Name of speaker, designation and organization | Date | Platform used |
1. | Gender equality in scientific career | Ms. Shyma Hamdan, Senior Research Assistant, Medical Research Council, Prion Unit, UCL Institute of Prion Diseases, University College London, London, UK | 09.03.2020 | Zoom Platform |
2. | Career as a pharmacist in the UK for women/girls | Mrs. Rita Patel Registered Pharmacist, London, UK | 09.03.2020 | Zoom Platform |
3. | World of medical devices | Mr. Gaurav Kapila Senior Specialist Global Regulatory Affairs Abbott Laboratories (Molecular Division) Des Plaines, Illinois, USA | 07.08.2020 | Zoom Platform |
4. | International Yoga Day Webinar | Isha Yog Center Koimtur TM | 21.06.2021 | Zoom Platform |
FACILITIES
List of Major Equipment
Name of the equipment for animal (rat/mice) study | Pharmacological activity for which the equipment/apparatus is used |
Plus maze apparatus | Anxiolytic activity |
Y maze apparatus | Anxiolytic activity |
Electroconvulsiometer | Anticonvulsant activity |
Pole climbing apparatus | Antipsychotic activity |
Condition preference apparatus | Learning and memory skill |
Stereotaxy apparatus | Intracerebrovascular canulation |
Digital plethysmometer | Anti-inflammatory activity |
Tail flick apparatus | Anti-inflammatory and analgesic activity |
Analgesiometer (Hot plate apparatus) | Analgesic activity |
Rota rod apparatus (Grip strength apparatus) (repair) | Muscle relaxant activity |
Actophotometer | Locomotor activity |
Metabolic cage | Diuretic activity |
Organ bath (Isolated tissue preparation tank) | Identification of receptor on which new drug acts |
Other equipments | Uses |
Bioanalyser | Complete blood count, lipid profile, other markers |
Spirometer | Vital capacity |
Blood pressure apparatus | Blood pressure measurement |
Stethoscope | Heart rate measurement |
Blood sugar kit | Blood sugar level measurement |
Thermometer | Temperature measurement |
Facilities
